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Ice crystals form and physically damage the peptide chains

140 OberbauerE.UrmannC.SteffenhagenC.BielerL.BrunnerD.FurtnerT.et al (2013)

Lactobacillus plantarum HAC01 ameliorates type 2 diabetes in high-fat diet and streptozotocin-induced diabetic mice in association with modulating the gut microbiota